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Since I updated to TB 45 I noticed that the Add-on works in the Addres book, but not in main menu, statusbar etc. The commands does nothing. Auto sync seems to not work as well.

Questa recensione riguarda una versione precedente (2.0.10) del componente aggiuntivo. 

I just tried out TB 45 with versions 2.0.10 and 3.0.0a3pre and both seem to work from the main TB window.

Could you e-mail me the log file?

UPDATE:
Thanks for sending me the log and error console screenshot!

I believe I've identified the problem and have released updates to gContactSync (2.0.11) and Contact Photos (1.1.12). If you need it to work before the update is reviewed you can disable all other add-ons and restart Thunderbird.