However, I've noticed something:
I was updating my blog on WordPress. My up&down arrows are vertically set and they were very close by the WP Update button. Despite I clicked the WP Update button outside of the up&down arrows, the WP Update button didn't work whatever I tried. (Also, on that particular WP edit page there was no place to move the frame away from the arrows.)
I think there are more blind spots around the arrows than I thought.