Thunderbird add-ons that I've either used for years, or tested and highly suggest.
Blocks annoying video ads on YouTube, Facebook ads, banners and much more.
Adblock Plus blocks all annoying ads, and supports websites by not blocking unobtrusive ads by default (configurable).
Organize your schedule and life's important events in a calendar that's fully integrated with your Thunderbird email. Manage multiple calendars, create your daily to do list, invite friends to events, and subscribe to public calendars.
Restyle the web with Stylish, a user styles manager. Stylish lets you easily install themes and skins for Google, Facebook, YouTube, Orkut, and many, many other sites. You can even customize Firefox and other programs themselves.
Adds some tools to import and export folders and messages
This extension allows you to export your saved passwords and disabled login hosts using XML or CSV files that can be imported later.
Personas are free, easy-to-install "skins" for Firefox. Personas Plus extends that built-in functionality to give you even more control and easier access to new, popular, and your own favorite Personas.
OpenPGP message encryption and authentication for Thunderbird and SeaMonkey.
Theme Font & Size Changer lets you change the global font size and font family used for the user interface in Firefox. Design your browser with your favorite font.
Adds the ability to create and edit entries in the password manager.
Adds toolbar buttons to the customize toolbar window in several programs including Firefox, Thunderbird and SeaMonkey. Some of the buttons make commonly preformed actions quicker, others add new functionality.
Allows URI texts written in webpages to be loaded by double clicks.
FoxClocks shows times around the world - or just your local time - at the bottom of your browser. It deals with daylight saving time so you don't have to.
This 15KB restartless add-on will add a "File" -> "Restart" menu item and a ctrl/cmd + alt + r hotkey to restart Firefox or Seamonkey.