PriceBlick has been a great way to make sure I get the best deals on various things, from computer parts to household items. Normally, I'll just browse wherever I'm most comfortable for the good in questions (Monoprice, Newegg, Amazon, etc), and let PriceBlick show me if there's a better deal on another site, sometimes things like Rakuten or B&H, which I don't browse frequently, yet save me a lot of money nonetheless.
My only issues with it are that (1) sometimes it prioritizes eBay listings, which I'm normally not interested in, and (2) sometimes it seems to not be able to find some items on competing sites--a problem I mostly have while browsing for computer parts on Amazon.
But despite these minor flaws, I wholeheartedly recommend PriceBlink to anyone intersted in getting the best browsing experience and the best price. =)