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Real Time with Bill Maher is a talk show that airs weekly on HBO, hosted by comedian and political satirist Bill Maher. Much like his previous series Politically Incorrect on Comedy Central and later ABC, Real Time features a panel of guests who discuss current events in politics and the media. Unlike the previous show, guests are usually more well-versed in the subject matter: more experts such as journalists, professors and politicians participate in the panel, and fewer actors and celebrities are included. Additionally, many guests appear via satellite.

Real Time is a weekly hour-long program with a studio audience, airing live on Friday nights at 10:00 pm EST. It originates from Studio 33 ("The Bob Barker Studio") at CBS Television City in Los Angeles. In addition, a 10- to 15-minute "Overtime" segment quickly follows the show on YouTube (Live Streams) which answers questions posted by viewers through HBO's online website for the show. Prior to 2009, approximately 12 new weekly episodes aired from February to early May, followed by another such set of new episodes from late August to November. In 2009, the show began airing as one continuous season.

HBO has renewed Real Time through 2020, for its 16th, 17th, and 18th seasons.