⚠️Beware of sketchy perms for what should just be an email signer.

I am voting one-star only to be visible with the bad votes because it almost made me not trying it out:
Contrary to the tone here, it works on Firefox/Linux with native gpg very well (current openSUSE Tumbleweed here).
Follow these instructions: https://github.com/mailvelope/mailvelope/wiki/Mailvelope-GnuPG-integration
Yes, it needs creating one file by hand.

Does not work at all with GPG on Linux.
EDIT: You have to follow https://github.com/mailvelope/mailvelope/wiki/Mailvelope-GnuPG-integration. You may also have to install from GitHub. This was not linked at all on the extension description or in the extension itself, hence the three stars.

FR : Mailvelope est un non-sens. Thunderbird est beaucoup plus pratique et efficace. Fonctionne bien avec Gmail. Mais avec Yahoo et Outlook il n'est pas possible d'insérer une pièce jointe.

US : Mailvelope is a nonsense Thunderbird is much more convenient and efficient.
Work well with Gmail. But with Yahoo and Outlook it's not possible to insert an attachment.

Great tool, super easy to install and use!